Scientific paperStudies in management of the contaminated wound: III. Assessment of the effectiveness of irrigation with antiseptic agents☆
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Initial Management of Traumatic Wounds
2017, Veterinary Clinics of North America - Small Animal PracticeCitation Excerpt :Wound irrigation is an important aspect of wound management; it helps to decrease bacterial contamination and physically removes foreign bodies, debris, and any other loose material from the wound.27–29 Cleaning of the clipped area is beneficial, but inadvertent spillage of antiseptics into the wound should be avoided because it causes an inflammatory response, increasing the wound's susceptibility to bacterial infection.30,31 In order to remove the wound debris, the force of the irrigation stream has to be greater than the adhesion forces holding the debris to the wound surface.28
Randomized, controlled trial of povidone-iodine to reduce simple traumatic wound infections in the emergency department
2016, InjuryCitation Excerpt :While different antiseptic agents are used for wound cleansing and irrigation in primary care, the choice of the best treatment, including elimination of skin disinfection by means of topical antiseptics, is still controversial and further randomized clinical trials are needed to provide more information about true effect of antiseptics on infection rate and healing process of traumatic wounds. Previous studies showed that there is no significant difference between alcohol containing skin antiseptic agents and aqueous povidone iodine solution in traumatic wound infection prevention [33] although recent evidence on this issue is lacking. Our results also indicated significant association between the wound location and the rate of infections, in which upper and lower limbs indicated the highest rates of infections.
In Memoriam: A Tribute to Dr. Owen H. Wangensteen, the Greatest Teacher of Surgery During the 20th Century (1898-1981)
2007, Journal of Surgical ResearchCitation Excerpt :The development of a program for the history of medicine at the University of Minnesota did not occupy all of Dr. Wangensteen’s time following his retirement as Chairman of the Department of Surgery. His interests in the management of infected wounds in collaborative studies with me resulted in a series of landmark contributions addressing revolutionary advances in would repair [7–15]. In our studies of the biology of wound repair and infection, Dr. Wangensteen and I designed the first adhesive skin closure tape that could approximate the wound edges without the use of sutures.
Bacterial decontamination of surgical wounds treated with Lavasept<sup>®</sup>
2006, International Journal of Hygiene and Environmental HealthTap water for irrigation of lacerations
2002, American Journal of Emergency MedicineCitation Excerpt :The choice of suture material used for repair was left to the discretion of the treating physician. A variety of different irrigation solutions have been studied in an attempt to reduce the bacterial wound load and decrease the chance of infection.15-18 Disinfectants such as alcohol, providone-iodine, hydrogen peroxide, hexachlorophene, and chlorhexidine have been shown to cause tissue toxicity and impair wound healing.
A Rational Approach to the Outpatient Management of Lacerations in Pediatric Patients
1998, Current Problems in Pediatric and Adolescent Health Care
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This work was supported by a grant from Headquarters, U. S. Army Medical Research and Development Command, Office of the Surgeon General, Washington, D. C.
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From the Departments of Surgery and Pediatrics, University of Minnesota Hospitals, Minneapolis, Minnesota 55455.
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Present address: University of Texas Medical School, San Antonio, Texas.