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2003, ChestCitation Excerpt :Alternatively, a continuous naloxone infusion may be used (0.4 to 0.8 mg/h). Severe side effects to naloxone are rare, but pulmonary edema and seizures have been reported.228229230 Noncardiogenic pulmonary edema, which tends to occur in the first few hours after acute overdose, may be difficult to distinguish from aspiration pneumonitis with ARDS217; however, improvement is generally more rapid in opioid-induced pulmonary edema.
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