Abstract
TdP is a serious complication of AV block. We report a case of complete AV block with QT prolongation who had bouts of TdP resistant to lidocaine and isoproterenol. Temporary pacing could not be performed, because insertion of a pacing lead triggered TdP that deteriorated into ventricular fibrillation. Nicorandil, a potassium channel opener, shortened the QT interval and abolished TdP. This may suggest that potassium channel opening drugs are clinically effective against TdP associated with bradycardia-dependent QT prolongation.
MeSH terms
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Aged
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Anesthetics, Local / therapeutic use
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Anti-Arrhythmia Agents / therapeutic use*
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Bradycardia / etiology
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Cardiotonic Agents / therapeutic use
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Electrocardiography / drug effects
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Female
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Heart Block / complications*
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Humans
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Isoproterenol / therapeutic use
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Lidocaine / therapeutic use
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Nicorandil / therapeutic use*
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Potassium Channels / drug effects*
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Torsades de Pointes / drug therapy*
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Ventricular Fibrillation / etiology
Substances
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Anesthetics, Local
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Anti-Arrhythmia Agents
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Cardiotonic Agents
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Potassium Channels
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Nicorandil
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Lidocaine
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Isoproterenol