Abstract
The efficacy of oral concentrate in the rapid tranquilization of 159 acutely disturbed patients in a psychiatric emergency service was evaluated. Patients were randomly assigned to 1 of 10 treatment groups: 7 oral groups and 3 comparison intramuscular groups. Although intramuscular medication produced a faster response, concentrate also proved to be effective for rapid tranquilization. Side effects were benign and minimal. Age, sex, race, and diagnosis had no effect on outcome. The use of concentrate as a paradigm for treating acutely psychotic patients is discussed.
Publication types
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Clinical Trial
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Randomized Controlled Trial
MeSH terms
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Acute Disease
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Administration, Oral
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Adolescent
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Adult
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Aged
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Antipsychotic Agents / administration & dosage*
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Drug Administration Schedule
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Emergency Services, Psychiatric
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Female
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Haloperidol / administration & dosage
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Humans
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Injections, Intramuscular
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Male
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Middle Aged
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Psychiatric Status Rating Scales
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Psychotic Disorders / drug therapy*
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Psychotic Disorders / psychology
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Thioridazine / administration & dosage
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Thiothixene / administration & dosage
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Time Factors
Substances
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Antipsychotic Agents
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Thiothixene
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Haloperidol
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Thioridazine