User profiles for "author:D Fitzpatrick"

David R FitzPatrick

- Verified email at nhs.net - Cited by 47223

David Fitzpatrick

- Verified email at mu.ie - Cited by 5783

New insights into the classification and nomenclature of cortical GABAergic interneurons

…, D Feldmeyer, G Fishell, D Fitzpatrick… - Nature Reviews …, 2013 - nature.com
A systematic classification and accepted nomenclature of neuron types is much needed but
is currently lacking. This article describes a possible taxonomical solution for classifying …

Delayed union and nonunions: epidemiology, clinical issues, and financial aspects

DJ Hak, D Fitzpatrick, JA Bishop, JL Marsh, S Tilp… - Injury, 2014 - Elsevier
Fracture healing is a critically important clinical event for fracture patients and for clinicians
who take care of them. The clinical evaluation of fracture healing is based on both …

Paediatric genomics: diagnosing rare disease in children

CF Wright, DR FitzPatrick, HV Firth - Nature Reviews Genetics, 2018 - nature.com
The majority of rare diseases affect children, most of whom have an underlying genetic
cause for their condition. However, making a molecular diagnosis with current technologies …

[HTML][HTML] Evolution of pathogenicity and sexual reproduction in eight Candida genomes

G Butler, MD Rasmussen, MF Lin, MAS Santos… - Nature, 2009 - nature.com
Candida species are the most common cause of opportunistic fungal infection worldwide.
Here we report the genome sequences of six Candida species and compare these and …

[HTML][HTML] A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival

PP Lee, DR Fitzpatrick, C Beard, HK Jessup, S Lehar… - Immunity, 2001 - cell.com
The role of DNA methylation and of the maintenance DNA methyltransferase Dnmt1 in the
epigenetic regulation of developmental stage-and cell lineage-specific gene expression in …

The Human Phenotype Ontology project: linking molecular biology and disease through phenotype data

S Köhler, SC Doelken, CJ Mungall, S Bauer… - Nucleic acids …, 2014 - academic.oup.com
Abstract The Human Phenotype Ontology (HPO) project, available at http://www. human-
phenotype-ontology. org, provides a structured, comprehensive and well-defined set of …

[HTML][HTML] Genetic diagnosis of developmental disorders in the DDD study: a scalable analysis of genome-wide research data

CF Wright, TW Fitzgerald, WD Jones, S Clayton… - The Lancet, 2015 - thelancet.com
Background Human genome sequencing has transformed our understanding of genomic
variation and its relevance to health and disease, and is now starting to enter clinical …

Orientation selectivity and the arrangement of horizontal connections in tree shrew striate cortex

…, Y Zhang, B Schofield, D Fitzpatrick - Journal of …, 1997 - Soc Neuroscience
Horizontal connections, formed primarily by the axon collaterals of pyramidal neurons in
layer 2/3 of visual cortex, extend for millimeters parallel to the cortical surface and form …

[HTML][HTML] Natural history of alkaptonuria

C Phornphutkul, WJ Introne, MB Perry… - New England journal …, 2002 - Mass Medical Soc
Background Alkaptonuria, caused by mutations in the HGO gene and a deficiency of
homogentisate 1, 2-dioxygenase, results in an accumulation of homogentisic acid (HGA) …

Endothelium-dependent vasorelaxing activity of wine and other grape products

DF Fitzpatrick, SL Hirschfield… - American Journal of …, 1993 - journals.physiology.org
Current interest in the presumed benefits of wine in protecting against coronary heart
disease prompted us to investigate possible effects of various grape products on vascular …