Objectives: This paper sought to evaluate whether high sensitivity troponin (hs-cTnT) can
immediately exclude acute myocardial infarction (AMI) at a novel 'rule out'cut-off …

BACKGROUND: Although acute allergic reactions after ingestion of peanuts and tree nuts
are common, fatalities are rare. Other than patients with coexisting asthma, it is currently not …

There is intense interest in the identification of novel biomarkers which improve the
diagnosis of heart failure. Serum samples from 52 patients with systolic heart failure (EF< …

OBJECTIVE: Patient history and physical examination are widely accepted as cornerstones
of diagnosis in modern medicine. We aimed to assess the value of individual historical and …

Background The original Manchester Acute Coronary Syndromes model (MACS)'rules
in'and 'rules out'acute coronary syndromes (ACS) using high sensitivity cardiac troponin T …

Objective To study the efficacy of six embryo-selection algorithms (ESAs) when applied to a
large, exclusive set of known implantation embryos. Design Retrospective, observational …

Candoxatril (UK-79300) is the orally-active prodrug of candoxatrilat (UK-73967), the active
enantiomer of (±) candoxatrilat (UK-69578), a potent neutral endopeptidase (NEP) inhibitor …

Objective We aimed to derive and validate a clinical decision rule (CDR) for suspected
cardiac chest pain in the emergency department (ED). Incorporating information available at …

This retrospective, single site observational study aimed to delineate five abnormal
embryonic developmental phenotypes, assessing their prevalence, development potential …

BACKGROUND: Hypertension, hyperlipidaemia, diabetes mellitus, tobacco smoking and a
family history of premature coronary artery disease are known to be risk factors for the …