Vascular dementia (VaD) is the second commonest cause of dementia. Stroke is the leading
cause of disability in adults in developed countries, the second major cause of dementia and …

Background Nitric oxide (NO) has multiple effects that may be beneficial in acute stroke,
including lowering blood pressure, and promoting reperfusion and cytoprotection. Some …

Blood pressure (BP) is elevated in 75% or more of patients with acute stroke and is
associated with poor outcomes. Whether to modulate BP in acute stroke has long been …

Background Tranexamic acid can prevent death due to bleeding after trauma and post-
partum haemorrhage. We aimed to assess whether tranexamic acid reduces haematoma …

Background Intensive antiplatelet therapy with three agents might be more effective than
guideline treatment for preventing recurrent events in patients with acute cerebral …

Background High blood pressure is common in acute stroke and is a predictor of poor
outcome; however, large trials of lowering blood pressure have given variable results, and …

Objective To assess the association of baseline imaging markers of cerebral small vessel
disease (SVD) and brain frailty with clinical outcome after acute stroke in the Efficacy of Nitric …

This review argues that even with the tremendous advances in diagnostic neuroimaging that
the clinical skills involved in clinical neurology (ie, history, examination, localisation and …

Background and Purpose: Cilostazol, a phosphodiesterase 3'inhibitor, is used in Asia-
Pacific countries for stroke prevention, but rarely used elsewhere. In addition to weak …

Background: The impact on clinical outcomes of patient selection using perfusion imaging
for endovascular thrombectomy (EVT) in patients with acute ischemic stroke presenting …