Itraconazole is a triazole antifungal agent with a broad spectrum of activity. It is well tolerated
and highly efficacious, particularly because its main metabolite, hydroxy‐itraconazole, also …

Purpose. Economic evaluations of clinical pharmacy interventions are reviewed. Summary.
A variety of clinical pharmacy interventions have been assessed, but the body of evidence …

BACKGROUND AND AIMS: Catheter-related infection (CRI) is the most common and
serious complication for adult patients receiving home parenteral nutrition (HPN). Our aim is …

Background Recent literature revealed that medication histories obtained by physicians and
nurses are often incomplete. However, the number of patients included was often low. Study …

Objectives During extracorporeal membrane oxygenation (ECMO), drug disposition
changes significantly. Plasma concentrations are altered due to an expanded circulating …

Background: The presence of bone metastases in patients with metastatic renal cell
carcinoma treated with oral tyrosine kinase inhibitors (TKIs) is associated with poorer …

BACKGROUND: Augmented renal clearance in critically ill patients can result in
underdosing of life-saving drugs, potentially leading to therapeutic failure. To detect this …

Therapeutic drug monitoring of phenytoin is necessary to ensure therapeutic and nontoxic
levels. Hypoalbuminemia, renal failure, and interactions with other highly protein‐bound …

Purpose Discrepancies in preadmission medication (PAM) are common and potentially
harmful. Medication reconciliation is able to reduce the discrepancy rate, yet implementation …

Background In the critically ill, multiple drug therapies for acute and chronic conditions are
often used at the same time and adverse drug events occur frequently. Many …