Article Text

Download PDFPDF

Topical analgesia for superficial corneal injuries.
  1. A K Brahma,
  2. S Shah,
  3. V F Hillier,
  4. D McLeod,
  5. T Sabala,
  6. A Brown,
  7. J Marsden
  1. Royal Eye Hospital, Manchester, United Kingdom.


    OBJECTIVE--To assess the analgesic effects of a topical non-steroidal anti-inflammatory agent, flurbiprofen 0.03%, during healing after superficial corneal injuries. METHODS--401 patients treated for corneal abrasion in a five month period were randomly allocated to one of four treatment groups: polyvinyl alcohol alone (control), homatropine 2%, flurbiprofen 0.03%, or homatropine 2% followed by flurbiprofen 0.03%. Treatments were given for 48 h. Ocular pain was recorded on a visual analogue scale by the patients over the first 24 h, and use of oral analgesics was also recorded. Usable responses were received from 224 patients (55.8%). RESULTS--Patients treated with flurbiprofen had significantly lower pain scores for the 24 h duration of the study than controls (P < 0.05). CONCLUSIONS--Flurbiprofen eye drops provide more effective pain relief than traditional treatments for superficial corneal injuries.

    Statistics from

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.