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Anaphylaxis and monoamine oxidase inhibitors—the use of adrenaline
  1. M J Fenwick,
  2. C L Muwanga
  1. Accident and Emergency Department, Sunderland Royal Hospital, Kayll Road, Sunderland SR4 7TP
  1. Correspondence to: Mr Fenwick


A 67 year old woman taking a monoamine oxidase inhibitor (MAOI) presented to the accident and emergency department with an anaphylactic reaction to flucloxacillin. This case highlights the uncertainty regarding the use of adrenaline (epinephrine) in the context of concurrent MAOI use. A summary of the evidence is presented to clarify this.

  • adrenaline
  • monoamine inhibitors
  • anaphylaxis

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  • Conflict of interest: none.

  • Funding: none.