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The Lazarus phenomenon following recreational drug use
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  • Published on:
    Re: Use 10mg of naloxone before abandoning resuscitation of cardio-respiratory arrest caused by opia
    Dear Editor,

    While it is reasonable to use large doses of Naloxone as described in the BNF (the maximum dose recommended is 10mg), the National poisons information service recommend that dose is titrated to response. Naloxone however, has also been attributed to improving GCS in gamma-hydroxybutyrate and alcohol overdoses.

    Large doses of opiate antagonists may be used in simple opiate overdose, however it was not cle...

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    Conflict of Interest:
    None declared.
  • Published on:
    Use 10mg of naloxone before abandoning resuscitation of cardio-respiratory arrest caused by opiate
    Dear Editor,

    We read with interest and some sympathy the recent case report by Walker et al of an apparent 'Lazarus' phenomenon in which spontaneous circulation unexpectedly returned after abandoning resuscitation of a patient believed to have taken an opiate overdose [1]. In common with inner-city Emergency Departments the world over, heroin overdoses make up a significant proportion of our workload. It is establis...

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    Conflict of Interest:
    None declared.