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Tricyclic antidepressant overdose: a review
  1. G W Kerr1,
  2. A C McGuffie2,
  3. S Wilkie2
  1. 1Accident and Emergency Department, Ayr Hospital, Dalmellington Road, Ayr, Scotland
  2. 2Accident and Emergency Department, Crosshouse Hospital, Kilmarnock
  1. Correspondence to: Dr Kerr (gary.kerr{at}


Overdoses of tricyclic antidepressants are among the commonest causes of drug poisoning seen in accident and emergency departments. This review discusses the pharmacokinetics, clinical presentation and treatment of tricyclic overdose.

  • tricyclic antidepressant
  • overdose

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  • Funding: none.

  • Conflicts of interest: none.