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Gamma hydroxybutyrate (GHB) is a water soluble, naturally occurring, tetra-carbon molecule. It has intermittently found use as a hypnotic anaesthetic agent, in treatment for narcolepsy, as an anabolic agent, and more recently as a drug of abuse1–7 (also known as “fantasy”, “GBH”, etc (see box 1 ). Review of the literature refutes the suggestion that GHB is a safe “natural high”, with a number of fatalities from overdose now reported.8,9 Deaths occur from profound respiratory and cardiovascular depression.7–9 We report two cases of Fantasy overdose in association with a motor vehicle crash, the presenting symptoms of which prompted treating doctors to erroneously suspect serious intracranial pathology.
Box 1 Street synonyms for gamma hydroxybutyrate
Fantasy
Phantasy
Liquid ecstasy
Liquid gold
Liquid X
Cherry Meth
Soap
GBH
Case report
A 21 year old man and 20 year old woman were brought to the Trauma Unit of the Royal Adelaide Hospital after a motor vehicle crash.
The man was the restrained driver of a vehicle that had lost control and crashed into a stobie pole (see fig 1), at a speed in excess of 60 kph. There was at least 60 cm intrusion into the front passenger compartment. His GCS was estimated as 14 (E=4, V=4, M=6) at the scene, where he was aggressive and combative, bleeding from a 5 cm midline laceration to his forehead. On arrival, he remained uncooperative, and required restraint. Further examination showed abrasions to his right shoulder, with an …
Footnotes
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Funding: none.
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Conflicts of interest: none.