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Atypical antipsychotics not recommended for control of agitation in the emergency department
  1. K R Whelan1,
  2. P I Dargan1,
  3. A L Jones1,
  4. N O’Connor2
  1. 1National Poisons Information Service, Guy’s and St Thomas’ NHS Trust, London, UK
  2. 2Emergency Department, St Thomas’ Hospital, London, UK
  1. Correspondence to:
 Dr K Whelan
 National Poisons Information Service, Avonley Road, New Cross, London SE15 5ER, UK;

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We read with concern the article by Yildiz et al, regarding the recommended use of atypical antipsychotics for the control of agitated patients in the emergency department.1 Our concern rests mainly with the control of agitation secondary to drug ingestion, particularly sympathomimetic drugs of misuse (cocaine, MDMA “ecstasy”, and amphetamines), and antidepressants (SSRIs, tricyclic antidepressants, MAOIs).

It can be difficult to distinguish with …

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