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Impact of a severe acute respiratory syndrome outbreak in the emergency department: an experience in Taiwan
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  • Published on:
    Re: Bonferroni correction for multiple comparisons

    Dear Editor

    I would like to thank Dr Shyr-Chyr Chen (1) for his warning about Bonferroni adjustments in multi comparisons about the article by Chen et al. (2). But to accentuate the some disadvantages of Bonferroni adjustment is required for the readers to interpret the results of the study better.

    We use the alpha level (0,05) to accept or refuse the null hypotesis. When more than 2 independent...

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    Conflict of Interest:
    None declared.
  • Published on:
    Bonferroni correction for multiple comparisons
    • Shyr-Chyr Chen, Associate Professor
    • Other Contributors:
      • Zui-Shen Yen, Shey-Ying Chen, and Chiung-Yuan Hsu

    Dear Editor

    We read with great interest the paper by Chen et al [1]. However, we believe there is a serious methodological error in the interpretation of the results.

    They did not apply Bonferroni correction when they made multiple comparisons between two groups. The Bonferroni correction is a statistical adjustment for the multiple comparisons [2,3]. The alpha level used in the study was 0.05 and they m...

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    Conflict of Interest:
    None declared.