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Aetiology of cerebral oedema in diabetic ketoacidosis
  1. A F T Brown
  1. Department of Emergency Medicine, Royal Brisbane Hospital, Herston, Brisbane, Queensland 4029, Australia;

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    The excellent evidence based review of the emergency management of diabetic ketoacidosis (DKA) in adults by Hardern and Quinn perpetuates the premise that “unnecessarily large volumes of intravenous fluids should be avoided because of the high case fatality rate of cerebral oedema”.1 This presupposes that the rate of fluid delivery is causally related to the development of cerebral oedema, which has not been proved. …

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