Several commonly prescribed antibiotics are known to interact with warfarin, increasing its anticoagulant effect by different mechanisms. Retroperitoneal bleeding with consequent haematoma is recognised as a complication of over-anticoagulation. Consequences, which are potentially fatal, include hypovolaemic shock and compression of retroperitoneal structures such as the ureter and inferior vena cava.
- CT, computed tomography
- INR, international normalised ratio
- IVC, inferior vena cava
- PE, pulmonary embolism
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Competing interests: there are no competing interests