Article Text

This article has a correction. Please see:

Download PDFPDF
Beware of prosthetic valve thrombosis despite therapeutic anticoagulation
  1. Paul William Xavier Foley1,
  2. Raj Sharma2,
  3. Paul R Karla1
  1. 1St Mary’s Hospital, Portsmouth, Hampshire, UK
  2. 2Department of Cardiology, Ealing District Hospital and Hammersmith Hospital, Ealing Hospital NHS Trust, Southall, London, UK
  1. Correspondence to:
 Dr P W X Foley
 St Mary’s Hospital, Milton Road, Portsmouth PO6 3AD, UK; paulfoley{at}


Patients with mechanical heart valves require anticoagulation within carefully controlled ranges to prevent valve thrombosis, a life-threatening condition. The majority of doctors will be required to manage anticoagulation, often on a temporary basis such as during elective procedures. As long-term anticoagulation management moves away from specialised hospital clinics, there needs to be widespread awareness of the complications of sub-therapeutic international normalised ratios (INRs).

  • INR, international normalised ratio
  • PVT, prosthetic valve thrombosis

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.


  • Competing interests: None declared.

  • Informed consent was given by this patient for publication of this report and figure.

Linked Articles

  • Correction
    BMJ Publishing Group Ltd and the British Association for Accident & Emergency Medicine