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Leptospirosis pulmonary haemorrhage: a diagnostic challenge
  1. M Dall’Antonia1,
  2. G Sluga2,
  3. S Whitfield1,
  4. A Teall1,
  5. P Wilson3,
  6. D Krahé4
  1. 1
    Queen Elizabeth Hospital NHS Trust, Woolwich, London, UK
  2. 2
    Department of Microbiology, King’s College Hospital, London, UK
  3. 3
    Barts and the London NHS Trust, London, UK
  4. 4
    Homerton University Hospital NHS Foundation Trust, London, UK
  1. Dr M Dall’Antonia, Queen Elizabeth Hospital NHS Trust, Stadium Road, Woolwich, London, SE184QH, UK; mdallantonia{at}


Leptospirosis is a re-emerging zoonosis with worldwide distribution. Antibiotic treatment is available, but leptospirosis is rarely suspected due to the non-specific clinical presentation, and is also underreported due to the difficulty in confirming the diagnosis. The syndrome of leptospirosis pulmonary haemorrhage is increasingly described; it is severe and can present without the classical manifestations of Weil’s disease. We discuss two cases of leptospirosis with pulmonary haemorrhage; both our patients experienced a dramatic deterioration hours after their admission, and required emergency intubation and intensive therapy unit support. Massive haemoptysis is a life threatening complication of leptospirosis, even outside tropical areas.

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  • Informed consent was obtained for publication of this case and figure.

  • Competing interests: None declared.

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