Responses
Other responses
Jump to comment:
- Published on: 29 April 2016
- Published on: 29 April 2016
- Published on: 29 April 2016Res omnes venena sunt, dosis sola facit venenumShow More
Overwhelmed by the sheer number of patients included, one is tempted to accept the conclusions made Peacock et al. in their recent paper [1] on the perceived risks of morphine in acute decompensated heart failure (ADHF).
However, in several ways their analysis is difficult to reconcile with published data and observations in the palliative care setting. It is surprising that in the rationale given for the admi...
Conflict of Interest:
None declared. - Published on: 29 April 2016Opiates should be avoided in acute decompensated heart failureShow More
Editor,
We were pleased to read Peacock et al’s paper warning of the dangers of morphine therapy in acute decompensated heart failure. [1] This retrospective review was the largest yet performed, with nearly 150000 patients in the database. The most concerning finding was an increased risk of mortality with an odds ratio of 5, despite extensive risk adjustment. Their conclusion that a prospective trial is neede...
Conflict of Interest:
None declared.