Responses

Download PDFPDF
Morphine and outcomes in acute decompensated heart failure: an ADHERE analysis
Compose Response

Plain text

  • No HTML tags allowed.
  • Web page addresses and e-mail addresses turn into links automatically.
  • Lines and paragraphs break automatically.
Author Information
First or given name, e.g. 'Peter'.
Your last, or family, name, e.g. 'MacMoody'.
Your email address, e.g. higgs-boson@gmail.com
Your role and/or occupation, e.g. 'Orthopedic Surgeon'.
Your organization or institution (if applicable), e.g. 'Royal Free Hospital'.
Statement of Competing Interests

PLEASE NOTE:

  • Responses are moderated before posting and publication is at the absolute discretion of BMJ, however they are not peer-reviewed
  • Once published, you will not have the right to remove or edit your response. Removal or editing of responses is at BMJ's absolute discretion
  • If patients could recognise themselves, or anyone else could recognise a patient from your description, please obtain the patient's written consent to publication and send them to the editorial office before submitting your response [Patient consent forms]
  • By submitting this response you are agreeing to our full [Response terms and requirements]

Vertical Tabs

Other responses

Jump to comment:

  • Published on:
    Res omnes venena sunt, dosis sola facit venenum
    • Ulrich S. Schuler, Oncology and Palliative Care
    • Other Contributors:
      • Michelle Meredith-Stewart, Barbara Schubert, and Rainer Sabatowski

    Overwhelmed by the sheer number of patients included, one is tempted to accept the conclusions made Peacock et al. in their recent paper [1] on the perceived risks of morphine in acute decompensated heart failure (ADHF).

    However, in several ways their analysis is difficult to reconcile with published data and observations in the palliative care setting. It is surprising that in the rationale given for the admi...

    Show More
    Conflict of Interest:
    None declared.
  • Published on:
    Opiates should be avoided in acute decompensated heart failure

    Editor,

    We were pleased to read Peacock et al’s paper warning of the dangers of morphine therapy in acute decompensated heart failure. [1] This retrospective review was the largest yet performed, with nearly 150000 patients in the database. The most concerning finding was an increased risk of mortality with an odds ratio of 5, despite extensive risk adjustment. Their conclusion that a prospective trial is neede...

    Show More
    Conflict of Interest:
    None declared.