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001 IMPACT OF PREHOSPITAL THROMBOLYTIC TREATMENT ON REINFARCTION RATES: ANALYSIS OF THE MYOCARDIAL INFARCTION NATIONAL AUDIT PROJECT (MINAP)
S Horne1, C Weston2, T Quinn3, A Hicks4, L Walker5, R Chen6, J Birkhead5. 1Emergency Department, Royal Cornwall Hospital, Truro; 2School of Medicine, University of Wales, Swansea, Wales; 3Applied Research Group in Pre-hospital, Emergency and Cardiovascular Care, Coventry University, Coventry; 4Emergency Department, Derriford Hospital, Plymouth; 5National Institute for Clinical Outcomes Research, The Heart Hospital, Westmoreland Street, London; 6University College London, Gower Street, London
Background: Reinfarction following thrombolytic treatment for acute myocardial infarction is associated with increased mortality. Reinfarction is more common after early treatment. Against a background of increasing prehospital thrombolytic treatment, we used data from MINAP to examine the frequency and determinants of reinfarction following prehospital treatment.
Methods: An observational study of 35 356 cases of STEMI given thrombolysis is in 2005–6.
Results: For 22 391 patients (66.3%) the presence or absence of reinfarction during the hospital admission was recorded; 1460 (6.5%) suffered reinfarction. Those having reinfarction had earlier treatment whether prehospital or inhospital (interval from onset to treatment was (median) 85 against 97 min (p = 0.017) …
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