Methanol intoxication is infrequent even though it is easily obtainable. One of the complications in locomotor apparatus is the development of a compartment syndrome of the lower extremities. A case is reported of a 49-year-old man with a compartment syndrome in all compartments of both legs and the anterior compartment of both thighs due to methanol intoxication. The patient underwent a bilateral fasciotomy of the legs and thighs. He also had haemodialysis sessions because of acute renal insufficiency. After 4 weeks of haemodialysis, covering of the fasciotomies with cutaneous autograft and rehabilitation treatment, the patient was able to walk on his own again. Early recognition and treatment of compartment syndrome are essential to avoid complications.
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