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Best Evidence Topic reports
BET 1. LACTATE CLEARANCE A BETTER PREDICTOR OF MORTALITY THAN INITIAL LACTATE LEVEL
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Report by Dhurga Gnanasegaram, Specialist Registrar in Emergency Medicine
Search checked by Neill Hughes, Specialist Registrar in Emergency Medicine
Institution: Manchester Royal Infirmary, Manchester, UK
A short-cut review was carried out to establish whether lactate clearance is a better predictor of mortality than the lactate concentration at presentation. Three papers were found addressing the clinical question. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of these papers are tabulated. The clinical bottom line is that lactate clearance is indeed a …