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In local anaesthesia…
False. This is a particularly popular topic for small randomised controlled trials that often show statistical but not clinical significance (a difference on the 100 mm visual analogue scale of more than 20 mm).1 The best studies in adults2 and children3 do not show a benefit of buffering lignocaine.
True. A review of the historical and trial data shows that low-dose adrenaline (1 : 100 000 or less) reduces the need for tourniquets and does not cause digital …