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Is propofol a safe and effective sedative for relocating hip prostheses?
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  • Published on:
    Propofol is not safe for sedation for hip relocation
    • Keith J Anderson, Consultant Anaesthetist
    • Other Contributors:
      • Dr malcolm Sim, Dr Alex Puxty, Professor John Kinsella

    University Department of Anaesthetics Level 2, University Block Glasgow Royal Infirmary 10 Alexandra Parade Glasgow G31 2ER

    19 February 2009

    Dear Sir,

    We read with interest the clinically based study, on the use of propofol to sedate patients for relocation of hip prostheses in the emergency department.[1] The authors rightly point out that there are problems with the safety and efficacy of us...

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    Conflict of Interest:
    None declared.
  • Published on:
    Propofol is effective but not safe for relocating hip prostheses
    • Dr Keith J Anderson, Consultant Anaesthetist
    • Other Contributors:
      • Dr Alex Puxty, Dr Malcolm Sim, Professor John Kinsella

    We read with interest the clinically based study, on the use of propofol to sedate patients for relocation of hip prostheses in the emergency department [1]. The authors rightly point out that there are problems with the safety and efficacy of using midazolam, and conclude that the described technique is both effective and safe. In another paper by the same authors they demonstrate this technique of “sedation” has a bet...

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    Conflict of Interest:
    None declared.
  • Published on:
    Original Author's response to e-Letter

    Dear Sir

    We welcome the interest in our work1 from anaesthetic colleagues. We respond to their areas of concern in turn.

    Pre-procedural starvation is indeed controversial. ASA/RCoA fasting guidelines are designed for elective cases and not necessarily practical for Emergency Department patients who require early intervention, or in whom airway manipulation is rare. A more practical guideline exists2....

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    Conflict of Interest:
    None declared.
  • Published on:
    Is propofol a safe and effective sedative for relocating hip prostheses?
    • Marc Davison, Consultant Anaesthetist
    • Other Contributors:
      • Richard Stewart

    Dear Sir,

    We read with interest the recent article by Mathieu et al on the use of propofol as an effective sedative for relocating hip prosthesis (1). We would like however, to draw attention to several areas of concern.

    The authors administered doses of propofol up to 2 mg/kg. This is an anaesthesia-inducing dose of propofol, rightly recognised in the discussion. The fact that patients were not rou...

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    Conflict of Interest:
    None declared.