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Unilateral blindness with third cranial nerve palsy and abnormal enhancement of extraocular muscles on magnetic resonance imaging of orbit after the ingestion of methanol
  1. Tae Nyoung Chung,
  2. Sun Wook Kim,
  3. Yoo Seok Park,
  4. Incheol Park
  1. Department of Emergency Medicine, Yonsei University College of Medicine, Seoul, Korea
  1. Correspondence to Incheol Park, 250 Sungsan-Ro, Seodaemun-Gu, Seoul, Korea; incheol{at}


Methanol is generally known to cause visual impairment and various systemic manifestations. There are a few reported specific findings for methanol intoxication on magnetic resonance imaging (MRI) of the brain. A case is reported of unilateral blindness with third cranial nerve palsy oculus sinister (OS) after the ingestion of methanol. Unilateral damage of the retina and optic nerve were confirmed by fundoscopy, flourescein angiography, visual evoked potential and electroretinogram. The optic nerve and extraocular muscles (superior rectus, medial rectus, inferior rectus and inferior oblique muscle) were enhanced by gadolinium-DTPA on MRI of the orbit. This is the first case report of permanent monocular blindness with confirmed unilateral damage of the retina and optic nerve, combined with third cranial nerve palsy after methanol ingestion.

  • Methanol
  • poisoning
  • oculomotor nerve
  • toxicology
  • violence
  • non accidental

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  • Competing interests None.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.