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Emergency casebook
Amisulpride overdose: suggested management of prolonged QTc
  1. Richard J Stevenson
  1. Department of Accident and Emergency, Monklands District General Hospital, Airdrie, Lanarkshire, Scotland, UK
  1. Correspondence to Dr Richard J Stevenson, Accident and Emergency, Monklands District General Hospital, Airdrie ML6 0JS, Lanarkshire, Scotland, UK; richard.stevenson{at}nhs.net

Abstract

A case of amisulpride overdose is presented and its effect on prolonging the QT (corrected) interval is discussed. Amisulpride is used for the treatment of schizophrenia and part of its safety profile is that is has no effect on the QT interval in therapeutic doses. The efficacy of intravenous calcium in restoring the QT to normal is proposed.

  • Amisulpride
  • overdose
  • QT
  • toxicology
  • ECG
  • mental health, overdose
  • mental health, mental illness

https://doi.org/10.1136/emj.2009.087049

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    Footnotes

    • Competing interests None.

    • Patient consent Obtained.

    • Provenance and peer review Not commissioned; not externally peer reviewed.