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The use of propofol for procedural sedation and analgesia in the emergency department: a comparison with midazolam
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  • Published on: 7 December 2016
    high fentanyl doses - is this an error?

    Dear authors,

    In your intersting RCT of propofol versus midazolam sedation, you describe giving a fentanyl dose of 3mcg/kg, in conjunction with a titrated dose of propofol or midazolam.

    This appears a pretty large dose, compared to the procedural sedation literature, where the usual dose is 1 mcg/kg (min-max 0.5-2.0).[1-2]

    From previous research with propofol and midazolam in the Emergency Depa...

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    Conflict of Interest:
    None declared.