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Epinephrine: best evidence to date?
Sophia recommends a read of this Australian randomised double-blind placebo-controlled trial, and the accompanying editorial by Drs Soar and Nolan. The study authors conclude that patients who received epinephrine had a statistically improved likelihood of a return of spontaneous circulation (greater than 30 s), but no improvement in survival to hospital discharge (their primary outcome). Their discussion highlights some of the difficulties in conducting a randomised controlled trial, with adverse press reports, concerns from politicians and only one of five ambulance services being willing to participate. The study was left with too few patients, and was therefore underpowered to detect any statistically significant difference in survival to hospital discharge (Resuscitation 2011;82:1138–43).
Public access to automated external defibrillators (AEDs) has become more common, but is the pubic ready for these devices? A questionnaire study was carried out at the Central Railway Station in Amsterdam. The location was chosen to gain access to the views of a large and international population sample. Over 1000 participants from 38 different countries took part in the survey. The data collected from …