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Which of the following are true regarding paracetamol?
With therapeutic dosing, paracetamol peak plasma concentrations occur within 1 h.
Administration of 50 g activated charcoal within 2 h of paracetamol overdose reduces mortality rates when combined with N-acetylcysteine (NAC) given within 8 h of ingestion.
Activated charcoal adsorbs paracetamol but not orally administered NAC.
Both paracetamol and NAC cross the placenta.
Which of the following are true of N-acetylcysteine (NAC)?
Intravenous NAC is more effective than oral NAC for paracetamol overdose.
NAC initial dosing is both patient weight-based and proportional to the 4 h …
Provenance and peer review Not commissioned; not externally peer reviewed.
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