Article Text

Download PDFPDF
BET 2: Therapeutic hypothermia for cardiac arrest of asphyxial origin


A short-cut review was carried out to establish whether therapeutic hypothermia leads to improved neurological outcomes in adult patients who have sustained a cardiac arrest of asphyxial origin. Four studies were directly relevant to the question. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of these papers are shown in table 2. The clinical bottom line is that evidence for the use of therapeutic hypothermia in patients who are comatose following asphyxia is very limited, which precludes an evidence-based recommendation. A large, multicentre randomised controlled trial is necessary to answer this question. Our review has therefore highlighted an important area for further research.

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.