Article Text

Download PDFPDF

Randomised trial of the fascia iliaca block versus the ‘3-in-1’ block for femoral neck fractures in the emergency department
  1. Paul Reavley1,
  2. Alan A Montgomery2,
  3. Jason E Smith3,4,
  4. Simon Binks5,
  5. Judith Edwards1,
  6. Georgina Elder1,
  7. Jonathan Benger1,6
  1. 1Academic Department of Emergency Care, Bristol Royal Infirmary, Bristol, UK
  2. 2Nottingham Clinical Trials Unit, University of Nottingham, Nottingham, UK
  3. 3Emergency Department, Derriford Hospital, Plymouth, UK
  4. 4Academic Department of Military Emergency Medicine, Royal Centre for Defence Medicine (Research & Academia), Birmingham, UK
  5. 5Emergency Department, Wollongong Hospital, New South Wales, Australia
  6. 6Faculty of Health and Life Sciences, University of the West of England, Bristol, UK
  1. Correspondence to Dr Paul Reavley, Emergency Department, Bristol Royal Infirmary, Upper Maudlin Street, Bristol BS2 8HW, UK; paulreavley{at}


Introduction Femoral neck fractures are a common and painful injury. Femoral nerve blocks, and a variant of this technique termed the ‘3-in-1’ block, are often used in this patient group, but their effect is variable. The fascia iliaca compartment block (FIB) has been proposed as an alternative, but the relative effectiveness of the two techniques in the early stages of care is unknown. We therefore compared the FIB versus the 3-in-1 block in a randomised trial conducted in two UK emergency departments.

Methods Parallel, two-group randomised equivalence trial. Consenting patients >18 years with a femoral neck fracture were randomly allocated to receive either a FIB or a 3-in-1 block. The primary outcome was pain measured on a 100 mm visual analogue scale at 60 min. The between-group difference was adjusted for centre, age, sex, fracture type, pre-block analgesia and pre-block pain score.

Results 178 patients were randomised and 162 included in the primary analysis. The mean 100 mm visual analogue pain scale score at 60 min was 38 mm in the FIB arm and 35 mm in the 3-in-1 arm. The adjusted difference between the arms was 3 mm, with a 95% CI (−4.7 to 10.8) that excluded a clinically important difference between the two interventions.

Conclusions FIB is equivalent to the 3-in-1 block for immediate pain relief in adult neck of femur fractures.

Trial registration number ISRCTN16152419.

  • analgesia/pain control
  • anaesthesia
  • fractures and dislocations

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Linked Articles

  • Primary survey
    Steve Goodacre