Clinical introduction

A 54-year-old male diagnosed with chronic hepatitis C, and hepatocellular carcinoma (HCC) status post transarterial embolisation twice, presented to our Emergency Department (ED) due to progressive cutaneous dysesthesia over bilateral palms and soles after taking a new agent for the cancer twice a day for 6 days, in addition to his daily analgesic medication etoricoxib (60 mg). Clinical examination revealed skin lesions over his palms (figure 1) and feet (figure 2).