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Best evidence topic reports
BET 1: Does a normal D-dimer rule out cerebral venous sinus thrombosis (CVST)?
  1. Emma Smith,
  2. Varun Kumar
  1. Nottingham University Hospitals NHS Trust, Nottingham, UK
  1. Correspondence to Emma Smith; production.emj{at}bmjgroup.com

http://dx.doi.org/10.1136/emermed-2018-207777.1

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    Clinical scenario

    A 32-year-old woman presented to the emergency department (ED) with a history of occipital headache and intermittent blurred vision for the past 3 weeks. D-dimer performed on admission is within normal range. Can you safely rule out cerebral venous sinus thrombosis (CVST)?

    Three-part question

    In (patients presenting to and ED with suspected CVST) does a (normal D-dimer) rule out this condition?

    Search strategy

    NICE Healthcare interface Medline 1966–November 2016

    [ddimer.ti,ab] AND [exp INTRACRANIAL EMBOLISM/OR exp INTRACRANIAL THROMBOSIS/OR exp SINUS THROMBOSIS, INTRACRANIAL/OR exp CAVERNOUS SINUS THROMBOSIS/OR exp INTRACRANIAL EMBOLISM AND THROMBOSIS/OR exp LATERAL SINUS THROMBOSIS/OR exp SAGITTAL SINUS THROMBOSIS/OR (cerebral AND venous AND sinus AND thrombosis).ti,ab/OR (sinus AND thrombosis).ti,ab] AND [exp DIAGNOSIS/OR …

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    Footnotes

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Competing interests None declared.

    • Patient consent Not required.

    • Provenance and peer review Not commissioned; internally peer reviewed.