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In reply:PICO questions in systematic reviews
  1. Milan L Ridderikhof1,
  2. Markus Hollmann2
  1. 1 Emergency Department, Amsterdam UMC—Locatie AMC, Amsterdam, The Netherlands
  2. 2 Anaesthesiology, Amsterdam UMC—Locatie AMC, Amsterdam, The Netherlands
  1. Correspondence to Dr Milan L Ridderikhof, Emergency Department, Amsterdam UMC - Locatie AMC, Amsterdam, North Holland 1105 AZ, The Netherlands; m.l.ridderikhof{at}

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Dear Editor,

We would like to thank Amir-Behghadami and Janati for sharing their thoughts and comments on our systematic review.1 They emphasise that formulating a PICO question aids in optimising the structure of a systematic review.

We think it is important to adhere to the PRISMA guidelines for performing a systematic review. In the PRISMA statement, it is advised that a structured approach should be used in order to facilitate the …

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  • Contributors MLR drafted the manuscript and MH corrected and approved the draft.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Not required.

  • Provenance and peer review Not commissioned; internally peer reviewed.

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