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Dear editor in chief,
We have read an article written by Jang et al.1 The results of this paper and a previous study suggested that higher serum phosphate may be associated with higher mortality in individuals with sepsis.1 2 Several critical issues in the analysis should be considered in interpreting the results.
The authors performed a multivariate analysis to adjust for confounders; however, blood urea nitrogen (BUN) and lactate were not included. Studies showed that blood lactate levels and BUN were positively associated with poor …
Handling editor Roland Merchant
Contributors JZ and QZ contributed equally to this manuscript.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Patient and public involvement Patients and/or the public were not involved in the design, or conduct, or reporting, or dissemination plans of this research.
Patient consent for publication Not required.
Provenance and peer review Not commissioned; internally peer reviewed.
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