RT Journal Article
SR Electronic
T1 Migraine: pharmacotherapy in the emergency department
JF Journal of Accident & Emergency Medicine
JO Arch Emerg Med
FD BMJ Publishing Group Ltd and the British Association for Accident & Emergency Medicine
SP 241
OP 245
DO 10.1136/emj.17.4.241
VO 17
IS 4
A1 Anne-Maree Kelly
YR 2000
UL http://emj.bmj.com/content/17/4/241.abstract
AB Migraine can be a disabling condition for the sufferer. For the small number of patients who fail home therapy and seek treatment in an emergency department, there are a number of therapeutic options. This paper reviews the evidence regarding the effectiveness and safety of the following therapies: the phenothiazines, lignocaine (lidocaine), ketorolac, the ergot alkaloids, metoclopramide, the “triptans”, haloperidol, pethidine and magnesium. Based on available evidence, the most effective agents seem to be prochlorperazine, chlorpromazine and sumatriptan, each of which have achieved greater then 70% efficacy in a number of studies.