@article {Coats193, author = {T J Coats and M Heron}, title = {Does calcium cause the different effects of Gelofusine and Haemaccel on coagulation?}, volume = {23}, number = {3}, pages = {193--194}, year = {2006}, doi = {10.1136/emj.2005.024034}, publisher = {British Association for Accident and Emergency Medicine}, abstract = {Background: Gelofusine (which does not contain calcium) has a greater effect on coagulation than Haemaccel (which contains 6.25 mmol/l of calcium). This in vitro study was performed to assess whether calcium might be the cause of the different effects on coagulation. Methods: Three solutions were compared; (a) Gelofusine, (b) Gelofusine with calcium added to 6.25 mmol/l, and (c) Haemaccel. Thromboelastography (Sonoclot) was used to examine whole blood coagulation, with time to peak clot weight as the primary outcome measure. Results: There was no significant difference between the Gelofusine containing solutions. Both Gelofusine solutions gave a greater impairment of coagulation than the Haemaccel solution. Conclusions: The different effect of Gelofusine on coagulation compared with Haemaccel does not seem to be related to the different calcium contents of the solutions.}, issn = {1472-0205}, URL = {https://emj.bmj.com/content/23/3/193}, eprint = {https://emj.bmj.com/content/23/3/193.full.pdf}, journal = {Emergency Medicine Journal} }