PT - JOURNAL ARTICLE AU - A Sheth AU - P Cullinan AU - V Vachharajani AU - S A Conrad TI - Bolus thrombolytic infusion during prolonged refractory cardiac arrest of undiagnosed cause AID - 10.1136/emj.2005.029132 DP - 2006 Mar 01 TA - Emergency Medicine Journal PG - e19--e19 VI - 23 IP - 3 4099 - http://emj.bmj.com/content/23/3/e19.short 4100 - http://emj.bmj.com/content/23/3/e19.full SO - Emerg Med J2006 Mar 01; 23 AB - Acute myocardial infarction (AMI) and pulmonary embolism (PE) account for about 70% of cardiac arrest. Although thrombolytic therapy is an effective therapy for both AMI and PE, it is not routinely recommended during cardiopulmonary resuscitation (CPR) for fear of life threatening bleeding complications. Numerous case reports and retrospective studies have suggested a beneficial effect of thrombolytics in cardiac arrest secondary to AMI and PE; however, we present a case of successful use of bolus thrombolytics during CPR in a patient with undifferentiated cardiac arrest (undiagnosed cause) after prolonged conventional resuscitation without success.