TY - JOUR T1 - BET 3 JF - Emergency Medicine Journal JO - Emerg Med J SP - 166 LP - 168 DO - 10.1136/emj.2010.108324 VL - 28 IS - 2 A2 - , Y1 - 2011/02/01 UR - http://emj.bmj.com/content/28/2/166.abstract N2 - Report by: Daniel Horner, ST4 Emergency Medicine/Critical CareSearch checked by: Craig Ferguson, SpR Emergency MedicineInstitution: Manchester Royal Infirmary, Manchester, UKA short-cut review was carried out to establish whether treatment with intravenous magnesium would improve the clinical outcome after an aneurismal subarachnoid haemorrhage (SAH). Five papers including systematic reviews were directly relevant to the question. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of these papers are tabulated. The clinical bottom line is that prophylactic elevation of serum magnesium in aneurysmal SAH may improve outcome when given in addition to standard treatment.Three-part questionIn a patient presenting with [aneurysmal subarachnoid haemorrhage] does [early elevation of serum magnesium by administration of intravenous magnesium sulphate] lead to a reduction in [subsequent vasospasm incidence, morbidity or mortality rates]?Clinical scenarioA 40-year-old woman attends the emergency department as a standby call. Her partner gives you a history of acute headache followed by collapse and reduced conscious level. She is rapidly intubated and … ER -