RT Journal Article SR Electronic T1 Issues around conducting prehospital research on out-of-hospital cardiac arrest: lessons from the TOPCAT study JF Emergency Medicine Journal JO Emerg Med J FD BMJ Publishing Group Ltd and the British Association for Accident & Emergency Medicine SP 637 OP 638 DO 10.1136/emj.2009.087395 VO 27 IS 8 A1 Lyon, Richard M A1 Egan, Gerry A1 Gowens, Paul A1 Andrews, Peter A1 Clegg, Gareth YR 2010 UL http://emj.bmj.com/content/27/8/637.abstract AB Outcome from OHCA is primarily determined by prehospital events and meaningful clinical OHCA research must include data recorded in this setting. There is little evidence on which to base the practice of prehospital resuscitation and research in this area presents huge challenges but is required if survival from OHCA is to improve. This short report aims to provide a practical guide to performing prehospital research on OHCA, based on lessons learned from the Temperature Post Cardiac Arrest (TOPCAT) research; an observational study into OHCA.