TY - JOUR T1 - Theme: Ketamine use and abuse JF - Emergency Medicine Journal JO - Emerg Med J SP - 552 LP - 552 DO - 10.1136/emermed-2011-200128 VL - 28 IS - 7 AU - Michael Davey Y1 - 2011/07/01 UR - http://emj.bmj.com/content/28/7/552.abstract N2 - Which of the following are true regarding the pharmacokinetics and pharmacodynamics of ketamine?It may be administered therapeutically orally, intravenously, intramuscularly, subcutaneously, transrectally, intrathecally, intra-articularly, intranasally and transdermally.The ketamine-induced cataleptic state is typically accompanied by nystagmus with pupillary dilation, salivation, lacrimation, and spontaneous limb movements with increased overall muscle tone.Ketamine is hepatically metabolised.Ketamine has a small volume of distribution and slow clearance making it less suitable for continuous infusion.Which of … ER -