PT - JOURNAL ARTICLE AU - Kim Wild AU - Hugh Wilson TI - Cannabinoid hyperemesis AID - 10.1136/emj.01.2010.2605rep DP - 2012 Jan 01 TA - Emergency Medicine Journal PG - 67--69 VI - 29 IP - 1 4099 - http://emj.bmj.com/content/29/1/67.short 4100 - http://emj.bmj.com/content/29/1/67.full SO - Emerg Med J2012 Jan 01; 29 AB - A 21-year-old woman presented with a 4-week history of sudden onset vomiting, nausea and anorexia. Questioning revealed that she had a 7-year history of heavy cannabis use (smoking). She did not describe abdominal pain, change in bowel habit, antibiotic use, foreign travel or contact with gastroenteritis. Biochemistry results demonstrated mild metabolic derangement with a low potassium and a low bicarbonate, and urine toxicology was positive for cannabinoids. Other investigations, including a full blood count, renal function tests, liver function tests, a coagulation sample, an ECG, urinary β-hCG and a CT head scan, were all normal. A diagnosis of cannabinoid hyperemesis was made and her symptoms resolved after treatment with intravenous fluids, antiemetics and abstinence from cannabis. Since her discharge and abstinence she has had several relapses, each related to cannabis use and each resolving with abstinence. The patient is now seeking cognitive behavioural therapy to achieve permanent abstinence.