TY - JOUR T1 - BET 1: Silibinin in suspected amatoxin-containing mushroom poisoning JF - Emergency Medicine Journal JO - Emerg Med J SP - 76 LP - 77 DO - 10.1136/emermed-2015-205558.1 VL - 33 IS - 1 AU - Guillaume Lacombe AU - Maude St-Onge Y1 - 2016/01/01 UR - http://emj.bmj.com/content/33/1/76.2.abstract N2 - A shortcut review was carried out to establish whether silibinin is better than conservative management at reducing liver transplantation and death after poisoning with amatoxin-containing mushrooms. Thirty-eight papers were found in Medline and 86 in EMBASE using the reported searches. Of these, five presented the best evidence to answer the clinical question. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of these best papers are tabulated. It is concluded that the evidence is limited, but given the lack of alternative treatments in patients with suspected amatoxin-containing mushroom poisoning and the relatively few adverse effects, silibinin should be considered in some patients. ER -