Table 2

Comparison of clinical studies of insulin with glucose

ReferenceSample sizeDose of soluble insulinDose glucoseMean initial K (mmol/l)Peak reduction in K (mmol/l)Time of maximal action (min)Duration of effect (min)Hypoglycaemia (%)
*=mU/kg/min, †=mg/kg/min.
385*40 g6.30.760>600
51010U40 g6.71.060>36020
755*60 g4.280.8560>600
101210U25 g5.480.6545>6075
12105*5†5.620.9260>6050
172010U30 g>6.00.98180>3600
18910U25 g6.330.7660>6011