Table 10
Author, date and countryPatient groupStudy type (level of evidence)OutcomesKey resultsStudy weaknesses
Wells PS et al, 1998, Canada184 patients with either DVT or PE (34 had PE) deemed at low risk of complications randomised to self administration dalteparin or homecare nurse administration. All treated at homeProspective cohortRecurrent thromboembolic event in three month follow up3.6%Small number of patients with PE
Major haemorrhage2.0%
Minor haemorrhage5.1%
Death7.2% —11 died of metastatic carcinoma, one of sepsis and one MI
Kovacs MJ et al, 2000, Canada81 patients treated at home for pulmonary embolism. Further 27 managed at home after average 2.5 days in hospital.Prospective cohortRecurrent thromboembolic event in three month follow up5.6%Comparatively small numbers
Major haemorrhage1.9%
Death3.7%—none due to PE or bleed
Labas P et al, Slovakia, 2001 28 patients diagnosed with concurrent PE and DVT treated at homeProspective cohortDeathNoneNo details given regarding diagnostic criteria for PE