Table 1
Author, date and countryPatient groupStudy type (level of evidence)OutcomesKey resultsStudy weaknesses
Lammers RL et al, 2001, USA331 adult women presenting to ED or intermediate care centre with more than one symptom of a UTI.Prospective observational studySensitivity92%Only women
NPV83%No sample size analysis
Positive dipstick defined as detectable nitrite or leucocyte esterase
Prevalence 45.9%.
Gold standard urine culture
Bent S et al, 2002, USAAdult women from nine original studies involving patients with symptoms of an UTI presenting to outpatient clinics. Total number of patients 2331Meta-analysisSensitivity75%Some studies only included women
Likelihood of UTI in presence of dysuria and frequency without vaginal discharge is high>90%Only able to use data from some studies
Positive dipstick defined as detectable nitrite or leucocyte esteraseDifference in cut off level for positive urine culture (range 100–100,000 CFU/ml)
Prevalence 48%Some studies of poor quality
Gold standard of positive urine culture