Table 7

Treatment of asthma2

Moderate acute asthmaSevere acute asthma (or no response to treatment in moderate asthma)Life threatening acute asthma
Protect and maintain airway as necessary
 Position for comfort (usually sitting upright)
 Salbutamol 5 mg via oxygen driven nebuliser
 If PEFR>50–75% of normal, give prednisolone 40–50 mg orally
 Treat and leave if patient responds to treatment
 Arrange re-assessment, possibly by telephone, at a suitable time
 Consider referring to GP or specialist nurse for delayed follow up if patient requires further support or review of treatmentOxygen via non-rebreathing mask*
 Repeat salbutamol 5 mg nebuliser at 5 to 15 min intervals until symptoms are controlled*
 Administer prednisolone 40–50 mg orally or hydrocortisone 100 mg IV
 Consider treat and leave if patient fully responds to treatment and has adequate carer support
 If discharged, arrange re-assessment, possibly by telephone, at a suitable time
 Refer to GP for immediate appointmentOxygen via non-rebreathing mask*
 Start transportation to hospital
 Repeat salbutamol 5 mg nebuliser at 5 to 15 min intervals until symptoms are controlled*
 Administer prednisolone 40–50 mg orally or hydrocortisone 200 mg IV*
 Oxygen via non-rebreathing mask*
 Repeat salbutamol 5 mg nebuliser at 5–15 min intervals until symptoms are controlled*
 Ipratropium 0.5 mg via nebuliser (may be mixed with salbutamol)
 Consider intravenous crystalloids in the presence of dehydration