Table 3

Studies of serum prolactin in GTCS and pseudoseizure disorder. Studies meeting criteria for evaluation

StudySample (total patients)Reference diagnosisExperimental test criteriaComments
9Pritchard 198512Pseudoseizure(PRL) v 3 baselineTertiary neurology centre cohort, 10 of 12 received gold standard test (video EEG), 4 of 6 in seizure group were non-convulsive
10Collins 198335Pseudoseizure(PRL) v 3 baselineEEG monitoring, tertiary neurology centre cohort, no baseline values
11Alving 199858Pseudoseizure(PRL) v 3 baselineVideo EEG in 47 of 58, tertiary centre cohort, individual patient data not provided, baseline values taken too early
3Trimble 197814Pseudoseizure(PRL) v 3 baselineNo video EEG in pseudoseizure cohort, pseudoseizure diagnosis made clinically tertiary centre cohort
12Mehta 199469Pseudoseizure(PRL) v3 baselineAll patients had EEG, acute medical inpatient cohort, baseline values in only eight patients, individual patient data not supplied
13Laxer 198551Pseudoseizure(PRL) v 3 baselineTertiary centre, all had video EEG
14Hoppener 198218Pseudoseizure(PRL) v 3 baselineTertiary centre, none had EEG, timing of baseline values uncertain.
15Rao 198911Pseudoseizure(PRL) v 3 baselineTertiary centre, all had video EEG, individual patient data and baseline values unavailable for comparison, type of seizure unclear
16Abbott 19809Healthy volunteers simulating GTCS(PRL) v 3 baselineTertiary centre, none had EEG, no baseline value in pseudoseizure group
16Abbott 198052Age and sex matched controls in A&E department, none with seizure(PRL) v 3 baselineAccident and emergency department cohort
17Fisher 19918Pseudoseizure(PRL) v 3 baselineTertiary centre, all underwent video EEG, no baseline values.