Estimates of one eligible study of sensitivity and specificity of serum prolactin value (three times baseline within one hour of collapse) in detecting GTCS from non-cardiac non-convulsive syncope
| Sensitivity | Specificity | ||||
|---|---|---|---|---|---|
| Study | (true positives + false negatives) | Sensitivity | Study | (false positives + true negatives) | Specificity |
| 18 Anzola 1993 | 17/24 | 71% | 18 Anzola 1993 | 11/13 | 85% |
| SN = 0.71 (95%CI (0.49 to 0.87)) | SP = 0.85 (95%CI (0.55 to 0.98)) | ||||
| +ve Likelihood ratio = 4.60 (1.25 to 16.90) (Lr+ve >5, strong diagnostic evidence) | −ve Likelihood ratio = 0.35 (0.18 to 0.67) (Lr−ve <0.1 = convincing evidence) | ||||
| Post-test probability = 90% chance of a GTCS if test positive (RULE IN DIAGNOSIS of GTCS) | Post-test probability = 39% chance of GTCS event if test negative (RULE OUT DIAGNOSIS of GTCS) | ||||